Mr. Scott has been diagnosed with hemochromatosis. He reads the following information on medical websites. Hereditary hemochromatosis is a genetic disease that alters the body's ability to regulate iron absorption. Common symptoms include tiredness, joint pain, abdominal pain, skin darkening, hair loss, and weakness.
Hereditary hemochromatosis is usually caused by a common gene mutation known as C282Y. But other mutations that cause this disease have also been Identified, including one known as H63D.
A child who inherits two copies of a mutated gene (one from each parent) is highly likely to develop the disease. However, not all people who have two mutated copies develop signs and symptoms of hereditary hemochromatosis.
People who inherit only one copy of the mutated gene are carriers, but usually have no symptoms, or have very mild symptoms since one correct copy of the gene appears to adequately regulate iron absorption.
Which statement correctly summarizes this information?
- A. Hemochromatosis is a dominant genetic disease caused by a single mutation.
- B. Hemochromatosis is a recessive genetic disease, but is caused by a lack of iron.
- C. Hemochromatosis is a recessive genetic disease, but the expression differs in individuals.
- D. Hemochromatosis is a dominant genetic disease that can be caused by several different alleles.
Correct Answer & Rationale
Correct Answer: C
Hemochromatosis is indeed a recessive genetic disorder, meaning that two copies of the mutated gene are typically required for the disease to manifest. Option A incorrectly categorizes it as a dominant disease, which does not align with its genetic inheritance pattern. Option B misstates the condition, as hemochromatosis is characterized by iron overload, not a deficiency. Option D also misrepresents the disease; while there are different alleles involved, hemochromatosis is primarily recessive, not dominant, making option C the most accurate summary of the information.
Hemochromatosis is indeed a recessive genetic disorder, meaning that two copies of the mutated gene are typically required for the disease to manifest. Option A incorrectly categorizes it as a dominant disease, which does not align with its genetic inheritance pattern. Option B misstates the condition, as hemochromatosis is characterized by iron overload, not a deficiency. Option D also misrepresents the disease; while there are different alleles involved, hemochromatosis is primarily recessive, not dominant, making option C the most accurate summary of the information.
Other Related Questions
Scientists can indirectly observe temperatures and insolation (the Intensity or direct solar radiation) in the distant past by measuring oxygen isotope ratios in ice cores collected from polar ice. The graph presents data for the period from what ta200.000 years ago. What time period in the graph shows the greatest correlation between Milankovitch cycles and climate?
- A. 140,000-160,000 years ago
- B. 120,000-140,000 years ago
- C. 100,000-120,000 years ago
- D. 160,000-180,000 years ago
Correct Answer & Rationale
Correct Answer: C
The time period from 100,000 to 120,000 years ago exhibits the greatest correlation between Milankovitch cycles and climate, as evidenced by significant fluctuations in temperature and insolation reflected in the oxygen isotope ratios. This interval aligns closely with the timing of glacial and interglacial periods influenced by Earth's orbital changes. Options A and B show notable climate changes, but they do not align as strongly with Milankovitch cycles, indicating less correlation. Option D, while part of the broader glacial cycle, reveals less pronounced temperature shifts, making it less relevant to the question of correlation.
The time period from 100,000 to 120,000 years ago exhibits the greatest correlation between Milankovitch cycles and climate, as evidenced by significant fluctuations in temperature and insolation reflected in the oxygen isotope ratios. This interval aligns closely with the timing of glacial and interglacial periods influenced by Earth's orbital changes. Options A and B show notable climate changes, but they do not align as strongly with Milankovitch cycles, indicating less correlation. Option D, while part of the broader glacial cycle, reveals less pronounced temperature shifts, making it less relevant to the question of correlation.
which sentence describes a difference between artificial selection and natural selection?
- A. In natural selection, variation is heritable; in artificial selection, variation is not heritable.
- B. In natural selection, there is differential reproduction; in artificial selection, there is not differential reproduction.
- C. In natural selection, there is variation within the population of organisms; in artificial selection, there is no variation within the population or organisms.
- D. In natural selection, reproductive success is driven by naturally occurring processes; in artificial selection, reproductive success is driven by human-imposed processes.
Correct Answer & Rationale
Correct Answer: D
Natural selection occurs through naturally occurring processes where organisms with advantageous traits are more likely to survive and reproduce, leading to evolutionary change over time. In contrast, artificial selection involves human intervention, where specific traits are chosen for breeding based on human preferences. Option A is incorrect; both types of selection involve heritable variation. Option B misrepresents artificial selection, which also involves differential reproduction based on selected traits. Option C is inaccurate as artificial selection can still involve variation within the chosen traits. Thus, option D accurately highlights the fundamental distinction between the two processes.
Natural selection occurs through naturally occurring processes where organisms with advantageous traits are more likely to survive and reproduce, leading to evolutionary change over time. In contrast, artificial selection involves human intervention, where specific traits are chosen for breeding based on human preferences. Option A is incorrect; both types of selection involve heritable variation. Option B misrepresents artificial selection, which also involves differential reproduction based on selected traits. Option C is inaccurate as artificial selection can still involve variation within the chosen traits. Thus, option D accurately highlights the fundamental distinction between the two processes.
Why is the conclusion about gene variation among cheetahs from Sommer's research more valid than the conclusion from O'Brien's research?
- A. Sommer's research was conducted more recently than O'Brien's
- B. Sommer's research used a different population of cheetahs than O'Brien's
- C. Sommer's conclusion is about disease response, while O'Brien's is about skin grafts.
- D. Sommer's conclusion is based on examining the genes, while O'Brien's conclusion is based on acceptance of a skin graft.
Correct Answer & Rationale
Correct Answer: D
Sommer's conclusion is more valid as it directly examines gene variation, providing a clearer understanding of genetic factors influencing traits. This direct analysis allows for more reliable insights into gene functionality. In contrast, O'Brien's research focuses on skin graft acceptance, which, while informative, does not provide the same depth of genetic examination. Option A is incorrect as recency does not inherently validate research findings. Option B is misleading; differing populations may affect findings but do not necessarily validate one conclusion over another. Option C misrepresents the focus of the studies; both are relevant but differ in application rather than validity.
Sommer's conclusion is more valid as it directly examines gene variation, providing a clearer understanding of genetic factors influencing traits. This direct analysis allows for more reliable insights into gene functionality. In contrast, O'Brien's research focuses on skin graft acceptance, which, while informative, does not provide the same depth of genetic examination. Option A is incorrect as recency does not inherently validate research findings. Option B is misleading; differing populations may affect findings but do not necessarily validate one conclusion over another. Option C misrepresents the focus of the studies; both are relevant but differ in application rather than validity.
Which statement is a valid conclusion from the data?
- A. The male athletes used more energy than the female athletes after 30 minutes of exercise.
- B. Strenuous exercise is more difficult for male athletes than female athletes.
- C. The average increase in heart rate was lower for the females than for the males.
- D. All the females had a lower heart rate than the males after 30 minutes of exercise.
Correct Answer & Rationale
Correct Answer: C
Option C accurately reflects the data, indicating a measurable difference in heart rate between male and female athletes after 30 minutes of exercise. This conclusion is supported by the data trends, which typically show a higher average heart rate in males. Option A makes an assumption about energy expenditure without specific data to support it, making it invalid. Option B incorrectly suggests a subjective comparison of difficulty, which cannot be deduced from heart rate data alone. Lastly, Option D overgeneralizes by claiming that all females had lower heart rates than males, which is unlikely and not supported by typical statistical findings, as individual variations exist.
Option C accurately reflects the data, indicating a measurable difference in heart rate between male and female athletes after 30 minutes of exercise. This conclusion is supported by the data trends, which typically show a higher average heart rate in males. Option A makes an assumption about energy expenditure without specific data to support it, making it invalid. Option B incorrectly suggests a subjective comparison of difficulty, which cannot be deduced from heart rate data alone. Lastly, Option D overgeneralizes by claiming that all females had lower heart rates than males, which is unlikely and not supported by typical statistical findings, as individual variations exist.