Mr. Scott has been diagnosed with hemochromatosis. He reads the following information on medical websites. Hereditary hemochromatosis is a genetic disease that alters the body's ability to regulate iron absorption. Common symptoms include tiredness, joint pain, abdominal pain, skin darkening, hair loss, and weakness.
Hereditary hemochromatosis is usually caused by a common gene mutation known as C282Y. But other mutations that cause this disease have also been Identified, including one known as H63D.
A child who inherits two copies of a mutated gene (one from each parent) is highly likely to develop the disease. However, not all people who have two mutated copies develop signs and symptoms of hereditary hemochromatosis.
People who inherit only one copy of the mutated gene are carriers, but usually have no symptoms, or have very mild symptoms since one correct copy of the gene appears to adequately regulate iron absorption.
Which statement correctly summarizes this information?
- A. Hemochromatosis is a dominant genetic disease caused by a single mutation.
- B. Hemochromatosis is a recessive genetic disease, but is caused by a lack of iron.
- C. Hemochromatosis is a recessive genetic disease, but the expression differs in individuals.
- D. Hemochromatosis is a dominant genetic disease that can be caused by several different alleles.
Correct Answer & Rationale
Correct Answer: C
Hemochromatosis is indeed a recessive genetic disorder, meaning that two copies of the mutated gene are typically required for the disease to manifest. Option A incorrectly categorizes it as a dominant disease, which does not align with its genetic inheritance pattern. Option B misstates the condition, as hemochromatosis is characterized by iron overload, not a deficiency. Option D also misrepresents the disease; while there are different alleles involved, hemochromatosis is primarily recessive, not dominant, making option C the most accurate summary of the information.
Hemochromatosis is indeed a recessive genetic disorder, meaning that two copies of the mutated gene are typically required for the disease to manifest. Option A incorrectly categorizes it as a dominant disease, which does not align with its genetic inheritance pattern. Option B misstates the condition, as hemochromatosis is characterized by iron overload, not a deficiency. Option D also misrepresents the disease; while there are different alleles involved, hemochromatosis is primarily recessive, not dominant, making option C the most accurate summary of the information.
Other Related Questions
Placing solid ammonium nitrate, NH4NO3, in a container of water causes an endothermic reaction. The result is ammonium hydroxide, NH4OH, and nitric acid, HNO3. Which diagram shows the correct equation for the reaction?
- A. NH4OH + HNO3 → NH4NO3 + H2O + energy
- B. NH4NO3 + H2O + energy → NH4OH + HNO3
- C. NH4NO3 + H2O → NH4OH + HNO3 + energy
- D. NH4OH + HNO3 + energy → NH4NO3 + H2O
Correct Answer & Rationale
Correct Answer: B
The reaction involving solid ammonium nitrate and water is endothermic, meaning it absorbs energy. Option B accurately reflects this by showing ammonium nitrate and water reacting to form ammonium hydroxide and nitric acid while requiring energy input, consistent with the endothermic nature of the process. Option A incorrectly suggests that energy is released, which contradicts the reaction's endothermic characteristic. Option C also misrepresents the energy aspect, implying that energy is produced, which is not the case. Option D similarly indicates that energy is released, misaligning with the reaction's true nature.
The reaction involving solid ammonium nitrate and water is endothermic, meaning it absorbs energy. Option B accurately reflects this by showing ammonium nitrate and water reacting to form ammonium hydroxide and nitric acid while requiring energy input, consistent with the endothermic nature of the process. Option A incorrectly suggests that energy is released, which contradicts the reaction's endothermic characteristic. Option C also misrepresents the energy aspect, implying that energy is produced, which is not the case. Option D similarly indicates that energy is released, misaligning with the reaction's true nature.
Scientists can indirectly observe temperatures and insolation (the Intensity or direct solar radiation) in the distant past by measuring oxygen isotope ratios in ice cores collected from polar ice. The graph presents data for the period from what ta200.000 years ago. What time period in the graph shows the greatest correlation between Milankovitch cycles and climate?
- A. 140,000-160,000 years ago
- B. 120,000-140,000 years ago
- C. 100,000-120,000 years ago
- D. 160,000-180,000 years ago
Correct Answer & Rationale
Correct Answer: C
The time period from 100,000 to 120,000 years ago exhibits the greatest correlation between Milankovitch cycles and climate, as evidenced by significant fluctuations in temperature and insolation reflected in the oxygen isotope ratios. This interval aligns closely with the timing of glacial and interglacial periods influenced by Earth's orbital changes. Options A and B show notable climate changes, but they do not align as strongly with Milankovitch cycles, indicating less correlation. Option D, while part of the broader glacial cycle, reveals less pronounced temperature shifts, making it less relevant to the question of correlation.
The time period from 100,000 to 120,000 years ago exhibits the greatest correlation between Milankovitch cycles and climate, as evidenced by significant fluctuations in temperature and insolation reflected in the oxygen isotope ratios. This interval aligns closely with the timing of glacial and interglacial periods influenced by Earth's orbital changes. Options A and B show notable climate changes, but they do not align as strongly with Milankovitch cycles, indicating less correlation. Option D, while part of the broader glacial cycle, reveals less pronounced temperature shifts, making it less relevant to the question of correlation.
Which statement describes a weakness of the investigation in the passage?
- A. None of the hypotheses are directly related to the ice core data.
- B. The Greenland ice sheet is far away from the site of the explosion in Russia.
- C. Several of the hypotheses rely on unproven processes or estimated values.
- D. A few micrograms of ammonia is insufficient evidence for a conclusion.
Correct Answer & Rationale
Correct Answer: C
Option C highlights a significant weakness, as relying on unproven processes or estimated values can lead to unreliable conclusions, undermining the investigation's credibility. Option A is incorrect because hypotheses can be related to data in broader contexts, even if not directly. Option B misrepresents the geographical relevance; distance alone does not invalidate the connection between the ice core data and the explosion. Option D, while suggesting a concern about evidence quantity, does not address the fundamental issue of reliance on unproven processes that can skew the investigation's outcomes.
Option C highlights a significant weakness, as relying on unproven processes or estimated values can lead to unreliable conclusions, undermining the investigation's credibility. Option A is incorrect because hypotheses can be related to data in broader contexts, even if not directly. Option B misrepresents the geographical relevance; distance alone does not invalidate the connection between the ice core data and the explosion. Option D, while suggesting a concern about evidence quantity, does not address the fundamental issue of reliance on unproven processes that can skew the investigation's outcomes.
The graph shows results from a study that sought to determine average exposure to triclosan in the U.S. population. Which statement is supported by the results in the graph?
- A. Triclosan concentration does not vary significantly among different age groups.
- B. Increased levels of triclosan in urine are related to increased age.
- C. Triclosan concentration in urine is highest in the 30- to 39-year-old age group.
- D. People aged 20-29 likely use more products containing triclosan.
Correct Answer & Rationale
Correct Answer: C
The data indicates that the highest triclosan concentration in urine occurs in the 30- to 39-year-old age group, supporting option C. This finding highlights a specific peak in exposure among this demographic. Option A is incorrect as the graph likely shows variation in triclosan levels across age groups. Option B misinterprets the data; the graph does not suggest that triclosan levels increase with age. Option D assumes usage patterns without evidence from the graph, which focuses on urinary concentration rather than product usage.
The data indicates that the highest triclosan concentration in urine occurs in the 30- to 39-year-old age group, supporting option C. This finding highlights a specific peak in exposure among this demographic. Option A is incorrect as the graph likely shows variation in triclosan levels across age groups. Option B misinterprets the data; the graph does not suggest that triclosan levels increase with age. Option D assumes usage patterns without evidence from the graph, which focuses on urinary concentration rather than product usage.