Mr. Scott has been diagnosed with hemochromatosis. He reads the following information on medical websites. Hereditary hemochromatosis is a genetic disease that alters the body's ability to regulate iron absorption. Common symptoms include tiredness, joint pain, abdominal pain, skin darkening, hair loss, and weakness.
Hereditary hemochromatosis is usually caused by a common gene mutation known as C282Y. But other mutations that cause this disease have also been Identified, including one known as H63D.
A child who inherits two copies of a mutated gene (one from each parent) is highly likely to develop the disease. However, not all people who have two mutated copies develop signs and symptoms of hereditary hemochromatosis.
People who inherit only one copy of the mutated gene are carriers, but usually have no symptoms, or have very mild symptoms since one correct copy of the gene appears to adequately regulate iron absorption.
Which statement correctly summarizes this information?
- A. Hemochromatosis is a dominant genetic disease caused by a single mutation.
- B. Hemochromatosis is a recessive genetic disease, but is caused by a lack of iron.
- C. Hemochromatosis is a recessive genetic disease, but the expression differs in individuals.
- D. Hemochromatosis is a dominant genetic disease that can be caused by several different alleles.
Correct Answer & Rationale
Correct Answer: C
Hemochromatosis is indeed a recessive genetic disorder, meaning that two copies of the mutated gene are typically required for the disease to manifest. Option A incorrectly categorizes it as a dominant disease, which does not align with its genetic inheritance pattern. Option B misstates the condition, as hemochromatosis is characterized by iron overload, not a deficiency. Option D also misrepresents the disease; while there are different alleles involved, hemochromatosis is primarily recessive, not dominant, making option C the most accurate summary of the information.
Hemochromatosis is indeed a recessive genetic disorder, meaning that two copies of the mutated gene are typically required for the disease to manifest. Option A incorrectly categorizes it as a dominant disease, which does not align with its genetic inheritance pattern. Option B misstates the condition, as hemochromatosis is characterized by iron overload, not a deficiency. Option D also misrepresents the disease; while there are different alleles involved, hemochromatosis is primarily recessive, not dominant, making option C the most accurate summary of the information.
Other Related Questions
Sommer's research concludes that cheetahs have sufficient genetic diversity to respond to common diseases, but may still be at risk of new diseases. Which statement from the passage supports this conclusion?
- A. Major histocompatibility complex (MHC) genes are used by the body to identify self from non-self...
- B. The variation in MHC genes in cheetahs is still smaller than that for other big cat species but appears to be sufficient...
- C. If any of the genetic factors are different, then the immune system of the individual...
- D. Sommer's research determined how many alleles are present on two different types of MHC genes...
Correct Answer & Rationale
Correct Answer: B
Option B directly supports Sommer's conclusion by highlighting that the variation in MHC genes among cheetahs, while less than in other big cats, is adequate for their immune response to common diseases. This indicates sufficient genetic diversity for disease management, aligning with the research's findings. Option A discusses the function of MHC genes but does not address their variation in cheetahs, making it less relevant. Option C mentions genetic factors affecting immune response but lacks specific information about cheetah genetic diversity. Option D focuses on the number of alleles without linking it to the implications for disease response, thus failing to support the conclusion effectively.
Option B directly supports Sommer's conclusion by highlighting that the variation in MHC genes among cheetahs, while less than in other big cats, is adequate for their immune response to common diseases. This indicates sufficient genetic diversity for disease management, aligning with the research's findings. Option A discusses the function of MHC genes but does not address their variation in cheetahs, making it less relevant. Option C mentions genetic factors affecting immune response but lacks specific information about cheetah genetic diversity. Option D focuses on the number of alleles without linking it to the implications for disease response, thus failing to support the conclusion effectively.
What is the relationship between the kinetic energy of the feather and of the hammer just before they hit the surface of the Moon?
- A. The hammer has more kinetic energy than the feather because it has a greater mass.
- B. Both objects have the same kinetic energy because they fell with the same velocity.
- C. The hammer has more kinetic energy than the feather because it will accelerate faster than the feather.
- D. Both objects have the same kinetic energy because gravity pulls on both objects equally.
Correct Answer & Rationale
Correct Answer: A
The hammer possesses more kinetic energy than the feather due to its greater mass, as kinetic energy is calculated using the formula KE = 0.5 * mass * velocity². While both objects fall at the same rate in a vacuum, their velocities are equal, but the hammer’s larger mass results in higher kinetic energy. Option B is incorrect because, although they have the same velocity, kinetic energy also depends on mass. Option C misrepresents the situation; both objects accelerate at the same rate in a vacuum. Option D is misleading; while gravity affects both equally, it does not determine kinetic energy, which also requires consideration of mass.
The hammer possesses more kinetic energy than the feather due to its greater mass, as kinetic energy is calculated using the formula KE = 0.5 * mass * velocity². While both objects fall at the same rate in a vacuum, their velocities are equal, but the hammer’s larger mass results in higher kinetic energy. Option B is incorrect because, although they have the same velocity, kinetic energy also depends on mass. Option C misrepresents the situation; both objects accelerate at the same rate in a vacuum. Option D is misleading; while gravity affects both equally, it does not determine kinetic energy, which also requires consideration of mass.
Which statement from the passage refutes Lavoisier's idea that heat is a fluid that leaves a hot substance and travels to a colder substance?
- A. He also found the brass filings produced from the drilling process contained enough heat to boil water while retaining their weight.
- B. James Joule discovered that heat could be produced by moving a wire through a magnetic field.
- C. Lavoisier demonstrated that oxygen was required for combustion.
- D. Count Rumford observed that the process of boring out cannons from brass cylinders continuously produced heat.
Correct Answer & Rationale
Correct Answer: A
Option A effectively refutes Lavoisier's notion of heat as a fluid by demonstrating that heat can be generated without the transfer of a fluid. The brass filings, despite retaining their weight, produced sufficient heat to boil water, indicating that heat can arise from mechanical processes rather than fluid movement. Option B, while highlighting Joule's discovery of heat production through motion, does not directly address Lavoisier's fluid concept. Option C focuses on combustion and oxygen's role, which is unrelated to the nature of heat itself. Option D describes an observation of heat generation during a mechanical process but does not emphasize the implications for Lavoisier's fluid theory as clearly as A does.
Option A effectively refutes Lavoisier's notion of heat as a fluid by demonstrating that heat can be generated without the transfer of a fluid. The brass filings, despite retaining their weight, produced sufficient heat to boil water, indicating that heat can arise from mechanical processes rather than fluid movement. Option B, while highlighting Joule's discovery of heat production through motion, does not directly address Lavoisier's fluid concept. Option C focuses on combustion and oxygen's role, which is unrelated to the nature of heat itself. Option D describes an observation of heat generation during a mechanical process but does not emphasize the implications for Lavoisier's fluid theory as clearly as A does.
Which hypothesis is suitable for this investigation?
- A. Body temperature, breathing rate, and heart rate depend on the health of the subject.
- B. Many of the body's systems respond to exercise.
- C. Body temperature, breathing rate, and heart rate increase with exercise.
- D. Subjects at rest have better health than subjects that exercise.
Correct Answer & Rationale
Correct Answer: C
Option C effectively addresses the investigation by predicting a specific relationship: that body temperature, breathing rate, and heart rate will increase with exercise. This hypothesis is testable and directly relates to physiological responses during physical activity. Option A is too broad, as it suggests a general relationship between health and various physiological metrics without focusing on exercise. Option B, while relevant, lacks specificity regarding the measurable changes in body temperature, breathing rate, and heart rate. Option D presents a misleading comparison, as it contradicts established knowledge about the benefits of exercise for health.
Option C effectively addresses the investigation by predicting a specific relationship: that body temperature, breathing rate, and heart rate will increase with exercise. This hypothesis is testable and directly relates to physiological responses during physical activity. Option A is too broad, as it suggests a general relationship between health and various physiological metrics without focusing on exercise. Option B, while relevant, lacks specificity regarding the measurable changes in body temperature, breathing rate, and heart rate. Option D presents a misleading comparison, as it contradicts established knowledge about the benefits of exercise for health.